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Progress and possibilities for patient-derived iPSCs and genetically engineered stem cells in cancer modeling and targeted therapies

S -nitrosoglutathione (GSNO) is an endogenous low-molar mass RSNO and serves as a stable reservoir and carrier of NO bioactivity capable of releasing NO or trans-nitrosylating protein thiols

Among these, LDHA and MDH1/2 are of particular importance, as they directly catalyze reactions that lead to the formation of L -2HG, but not the D -enantiomer, under hypoxic conditions (71)

Regenerating powder forms of GO is quite challenging compared to GO integrated into more stable materials

Masson MJ, Carpenter LD, Graf ML, Pohl LR

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