dihexa morris water maze water-maze Dihexa: Mechanism, Effects & Research

implications for intradiscal therapy

Hecquet S, Totoson P, Martin H, Prati C, Wendling D, Demougeot C, et al

This system entraps the active agent within a lipid-based vesicle, enhancing its stability during transit through the GI tract and improving its absorption by protecting the active agent from degradation, controlling its release, and promoting its passage across the intestinal barrier

The chronic inflammatory environment degrades existing collagen faster than the body can replace it, and the disorganized keratinocyte proliferation further disrupts normal tissue structure

Weekly check: Verify fridge temperature

Figure 5: Changes in the levels of A) IL-1-beta, B) TNF-alpha, and C) IL-10 in each of the four different experimental groups included in the first part of the study