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A panel reactive antibody test assesses the recipient's baseline allosensitization by measuring existing antibodies against a broad array of population HLA antigens

With the use of precursor ion scan, neutral loss scan and MRM, it can achieve superior selectivity, specificity and sensitivity with minimal background

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In addition, according to bioinformatics data, the ferroptosis-related factor APOE4 may be closely related to m6A methylation regulators in the brain tissue of AD patients (METTL3, METTL16, YTHDC2, and LRPPRC) (Du et al., 2021)