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In conclusion, ozone exposure leads to oxidative stress, which stimulates the purinergic receptor and GSK-3 response, activating the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) to produce the pro-inflammatory IL-1 and lowering IL-10, both of which give rise to cell death [23]

J Neurochem 114 , 112, (2010)

Tinnitus specific observations: While large-scale Phase III trials are ongoing, early clinical observations in smaller patient groups have noted improvements

Biochemical Medicine 28(2): 197203

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Those following a vegetarian or plant-based diet, who may get less dietary carnitine from food