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An increase in xanthine oxidase activity as a result of proteolytic cleavage of xanthine dehydrogenase has been proposed to play a key role in triggering oxidative stress and postischemic reperfusion injury (59, 60)

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Mitochondria are dynamic organelles that supply energy to the body and dysfunction is related to numerous kinds of disease, such as maternally inherited diabetes and deafness, the syndrome of metabolic defects, and autosomal dominant optic atrophy (44)

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Those who eat a primarily plant-based diet while on tirzepatide may benefit as well