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However, these studies are still clinically meaningful because they focus on practical outcomes such as transfusion frequency, fatigue, appetite, body weight, and overall functioning, which directly influence how patients feel and live

doi: 10.1186/s13018-019-1242-6

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In a clinical trial for weight reduction that included an intensive lifestyle intervention lead-in period (Study 3), 287 patients were treated with ZEPBOUND for up to 72 weeks