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This action of CHAC1, known as the blocker of NOTCH, effectively reduces the cell surface expression of the full-length NOTCH1 receptor, thus inhibiting the NOTCH1 signaling pathway and contributing to the suppression of T-ALL cell viability ( 6.9 Melanoma Melanoma is a type of skin cancer that arises from the melanocytes, the cells responsible for producing melanin, the pigment that gives skin its color

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