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doi: 10.1016/j.mehy.2004.03.021

It was identified that as the degree of ferroptosis increased, the proportion of TUNEL-positive cells significantly increased, suggesting that ferroptosis promoted HK-2 cell death under a high concentration of CaOx (Fig

5-Azacitidine is modified by nucleotide reductase and then phosphorylated by uridine cytidine kinase to form a triphosphate, 5-azacitidine triphosphate, which is integrated into the DNA sequence as a cytosine analog during DNA replication, thereby inhibiting DNA cytosine methylation (Rius et al., 2009)

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The study found that 5-amino-1MQ effectively slowed the growth of these cancer cells and even led to signs of cell death (apoptosis)