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J., Liang, D., Ellington, A

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Taking postmenopausal osteoporosis as an example, estrogen deficiency induces M1 polarization of macrophages by activating the Toll-like receptor 4 (TLR4)/Myeloid Differentiation Factor 88 (MyD88) signaling pathway

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When the homeostatic balance of copper ion levels is disrupted, such as through excess copper ions, this imbalance can trigger cellular toxicity and induce cell death via various pathways (15)

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Modulating its activity could offer avenues for mitigating the detrimental effects of radiation on the brain, making it a focal point in contemporary neurobiological research [32, 38]

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