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The deletion frequency at each nucleotide position was calculated as the number of reads with a deletion at that position divided by the total read count

Furthermore, Itch/AIP4 has been shown to mediate ubiquitylation-dependent degradation of Notch1 through lysosome [12]

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UVB drives metabolic rewiring and epigenetic reprograming and protection by sulforaphane in human skin keratinocytes