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The diagnosis of PFPT had been made based on clinical findings of circumscribed pigmentation localized on fungiform papillae of the tongue and also in association with dermoscopic findings

Carbas, B., Machado, N., Pathania, S., Brites, C., Rosa, E

SAH is rapidly broken down by the enzyme SAH hydrolase into adenosine and homocysteine (Hcy).38, 17

This represents a so far unexplored mechanism of how pathogens are able to reprogram their virulence and to precisely adjust their infectivity to the environment, i.e., the metabolic state, and to their own fitness and/or the fitness of the infected host cells

The sham surgery group (referred to as normal cartilage) was sacrificed at 12 weeks, and the only-defect groups with PBS injection (referred to as only-defect) were sacrificed at 4, 8, and 12 weeks when the injection groups were sacrificed

It must be assessed and closely monitored on an individual basis