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There are two situations here, namely short-term stress and long-term stress

The finding reframes a supposedly purely beneficial nutrient as also a microbial energy source with a possible dark side

Notably, animal models have demonstrated that transferring dysbiotic microbiota from CFS/ME patients to germ-free mice can induce fatigue-like behaviors, supporting a causal role for the microbiome in disease pathogenesis (Bansal et al., 2025)

The findings of our study showed that the administration of MSG for 28 days resulted in oxidative stress

Hernndez-Hernndez OT, Martnez-Mota L, Herrera-Prez JJ, Jimnez-Rubio G (2018) Role of estradiol in the expression of genes involved in serotonin neurotransmission: implications for female depression

doi: 10.3389/fphys.2022.795980 63 WeiYeZhuX-yWangKWangZ-r