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Apigenin (20 mg/kg) was also able to prevent the reduction in blood pressure and scratching behavior caused by anaphylaxis induced by antigen and Compound 48/80, however did not significantly affect blood flow [133]

10.1021/acs.jafc.0c02058 77 XieZ

When taken as prescribed, other popular lightening agents, including kojic acid, vitamin C, and alpha hydroxy acids (AHAs) are generally safe, however, some people may experience sensitivity or discomfort from them

First, Sensing and Destruction: COFs, equipped with precisely integrated sensitizing units, efficiently respond to external stimuli (e.g., light, ultrasound, radiation) or endogenous triggers (e.g., H 2 O 2 ), generating intense local biochemical effects such as bursts of ROS, hyperthermia, or DNA damage ( Figure 2 ) (155, 156, 166)

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In this tissue, GSSG concentration increased 2 times in comparison to the control