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J Biol Regul Homeost Agents 29 , 913923 (2015)

Always aim the needle at the vial wall and let the water trickle down gently

Cohort studies showed that metformin reduced the risk of dementia in T2DM patients by 35% over 8 years (Hsu et al., 2011), but a prospective study showed that metformin increased cognitive deterioration and risk of AD (Koo et al., 2019)

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On the other hand, the cooperative strategies in natural consortia, e.g., aggregation, DOL and metabolic flexibility, lay foundations to design inter-species interactions within synthetic communities