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4 Discussion Hypoxia have been associated with a number of pathological conditions, while HIFs are the main transcriptional factors tuning gene expression and orchestrating cellular function

These types of enzymes participate in the regulation of the oxidative and inflammatory state, and it has previously been considered as a factor that affects the disease activity

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doi: 10.7150/ijbs.120980

Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD study)

October 19, 2023: FDA authorized an extension to the shelf-life from 24 months to 30 months for certain lots of manufactured and labeled Gohibic (vilobelimab), which is currently authorized for the treatment of COVID-19 in certain hospitalized adults under EUA 118