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PMID 35691683

For severe deficiency, the AAFP recommends loading doses typically daily or every other day for one to two weeks followed by monthly maintenance injections

"Prospective Multicenter Clinical Trial of a Temperature-Controlled Subcutaneous Microneedle Fractional Bipolar Radiofrequency System for the Treatment of Cellulite," Dermatologic Surgery , 2018.

Prescription drugs: Some prescription drugs can be taken at the onset of a migraine, such as dihydroergotamine, which is best for attacks that tend to last longer than 24 hours

Are there clinical features of liver disease, myeloproliferative disorder (e.g., blood film changes of unexplained cytopenia, thrombocytosis, or leukocytosis), or another cancer (e.g., cachexia, constitutional symptoms fever, weight loss, night sweats)