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Therefore, we did not propose any adjustments in burden because we assumed the additional cost requirement will not add significant burden to the currently approved 10 hour per application burden estimate

It can occur in people as young as their 20s, but it's likely inherited.

They thus put forward the sulfite hypothesis, arguing that sulfite is the primary physiological sulfur acceptor for SQOR in the liver and heartproviding strong in vivo support for the classic Jorns model