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17, 66 Mice deleted of claudin-1 protein expression die premature owing to dehydration, suggesting a key function for this protein in regulating dermal barrier function

The mechanism of action is an improvement of the NF-B signalling pathway and a correction of the inflammatory environment of the ovarian tissue (114)

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The chronic inflammatory environment degrades existing collagen faster than the body can replace it, and the disorganized keratinocyte proliferation further disrupts normal tissue structure

Nat Immunol (2011) 12(5):40815

Better Mental Health: Proper levels of vitamin B12 are essential for maintaining healthy brain functions and preventing cognitive decline