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The peptide's biological activity depends entirely on maintaining the chelated copper ion in its Cu oxidation state, bound to the histidine and lysine residues through coordinate covalent bonds

Injection mixture containing Pcat-2prom3::cat-2::SL2::GFP (30 ng/uL), Pdat-1::cat-2::SL2::GFP (30 ng/uL), Phlh-17::cat-2::SL2::GFP (30 ng/uL), or Pelt-2::cat-2::SL2::GFP (30 ng/uL) together with the co-injection marker Pmyo-3::mCherry (5 ng/uL) were injected into CX11078 cat-2 (e1112) II

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Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders