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Description

J Biol Chem (2010) 285(42):3214150

Mechanistically, STING was shown to directly interact with YY1, inhibiting its nuclear translocation and consequently promoting transcription of lipocalin-2 (LCN2)

Further, the impairment in signaling was followed by increased production of resistin

The median eminence, a new oligodendrogenic niche in the adult mouse brain

Evidence suggests it may promote neuroprotection, regulate inflammation, and influence mood and cognition, with potential clinical relevance for neurodegenerative and psychiatric disorders

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