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Non-native disulfides are resolved by reduced PDIs, which are regenerated by GSH, leading to the formation of GSSG

Frontiers in Bioengineering and Biotechnology 10, 816362

Each deacetylation cycle of SIRT1 consumes one NAD molecule, producing acetyl-ADP-ribose (1-O-acetyl-ADP-ribose or 2- and 3-O-acetyl-ADP-ribose) and nicotinamide as byproducts (Liu et al., 2022a