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Moreover, limited solvent access and an apolar protein environment would contribute to the overall stabilization

Ferroptotic cell death could explain the dying back phenotype of the large neurons of the CDN and DRG observed in postmortem analyses (Said et al., 1986

The mitochondrial forms of this enzyme, MTHFD2 and MTHFD2L, can use either NAD + or NADP + as a cofactor, whereas the cytosolic form, MTHFD1, specifically uses NAD +

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This, in turn, resulted in significant growth inhibition of the tested cell lines (Fig