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In case of second trial (NCT04341675), the investigators have employed a randomized, double blind, placebo-controlled study design

To calculate isotopologue similarity scores ( S ISO ), we developed a scoring algorithm applicable for three types of metabolic scenarios which are based on the numbers of carbon and labeled isotopologues between metabolite pairs (Supplementary Fig

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Asparagine restriction enhances CD8+ T cell metabolic fitness and antitumoral functionality through an NRF2-dependent stress response

Weiss, R

The story is complex for two reasons