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To develop such therapies, a deeper understanding of both disease pathogenesis and mechanisms of barrier regulation must be reached

doi: 10.1136/emermed-2020-209980 357

PMID: 28266027

Key findings included: Statistically significant erectile responses at doses above 7 mg compared to placebo Onset of first erection occurring approximately 30 minutes post-administration Mean duration of adequate erection rigidity increasing from 18 minutes to 73 minutes at higher doses Efficacy in approximately one-third of men who had inadequate response to sildenafil Studies using subcutaneous administration (1.0-10.0 mg) in men with inadequate Viagra response demonstrated dose-dependent improvements in penile rigidity and erectile function

Huo S, Wang Q, Shi W, Peng L, Jiang Y, Zhu M

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