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Journal of Science and Medicine in Sport, 24 (1), 9297

In Peyers patches, which are inductive sites for IgA in the small intestine, retinoic acid production by DCs following microbial stimulation is likely one of the main drivers of CSR from IgM to IgA

Your liver produces glutathione naturally, but it's also found in high concentrations throughout your body's most vital organs: eyes, spleen, pancreas, and kidneys