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In age-related disorders and chronic diseases including Alzheimers disease (AD), decreasing intracellular GSH levels is mainly attributed to declining GCL activity [4, 5]

Understanding these nutritional challenges is essential for optimizing therapeutic outcomes while maintaining overall health

Bisdemethoxycurcumin, a novel potent polyphenolic compound, effectively inhibits the formation of amyloid aggregates in ALS-associated hSOD1 mutant (L38R)

doi: 10.7860/JCDR/2014/10258.5292 4 BarcelouxD

New data have since been added to this particular topic that seem to mainly support previous evidence on the unambiguous effect of flavanols on these crucial signaling pathways

This line of reasoning led to the hypothesis that pharmaceutical and/or nutraceutical manipulations that increase the availability of antioxidant substrates in the brain could be of therapeutic benefit