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while GSSG supplementation rescued roGFP2 re-oxidation, GSH had no influence on the periplasmic redox dynamics in dsbA (Fig

Shafabakhsh R, Mobini M, Raygan F, Aghadavod E, Ostadmohammadi V, Amirani E, et al

& Hagspiel, K

Western populations are uncommonly affected by severe niacin deficiency that results in pellagra, but individuals at risk of pellagra may have suboptimal niacin intake, such as cancer patients and those exposed to genotoxic agents such as ionizing radiation, ultraviolet radiation, and alkylating agents [444]

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In contrast, UC is characterized by persistent inflammation of the mucosal and submucosal layers of the colon, with the initial manifestation of the disease typically occurring in the rectum and subsequently extending gradually along the colon