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Description

Bannister, Jiang Li, Gavin E

We developed a heterologous, recombinant modified vaccinia virus Ankara prime and adjuvanted protein boost vaccine, containing regulatory protein EE2 and major capsid protein

Results A counter-selection system was engineered in Saccharomyces cerevisiae based on the known feedback inhibition of gamma-glutamylcysteine synthetase ( GSH1 ) gene expression, which is rate limiting for GSH synthesis: the GSH1 ORF and the counter-selectable marker GAP1 were expressed under control of the TEF1 and GSH-regulated GSH1 promoters, respectively

Activation of p53 by MDM2-inhibition sensitizes quiescent blast crisis CML stem/progenitor cells to Bcl-2 inhibitor- and tyrosine kinase inhibitor-induced cell death

10.1098/rsif.2009.0204 J

Abstract The notorious woody plant-degrading pathogen Lasiodiplodia theobromae is a major causal agent of peach gummosis, one of the prevalent and devastating trunk diseases to peach production