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An aliquot of 50 l of the collected sample was subjected to cytokine measurement via Luminex magnetic beads according to the Mouse LX-MultiDTM-31 protocol (Bio-Rad, Hercules, CA, USA

Given the current unresolved issue regarding a potential low B12/high folate interaction (see above), a case has been made for at least considering vitamin B12 food fortification, although randomized clinical trials are required to fully justify this (105)