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Specifically, the FDA says that to approve new or updated COVID-19 vaccines (boosters) for use in individuals who are not considered at higher risk (higher risk is defined as persons 65 or older or those with certain health conditions), vaccine makers will need to present evidence from randomized, placebo-controlled trials that demonstrate safety and efficacy

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At the same time, we have learned that other diseases related to the GBA mechanism of PD include SIBO, IBD, appendicitis, and even systemic diseases such as tuberculosis and diabetes (Li et al., 2021

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