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246,248 LTB 4 can enhance neutrophil accumulation in acute inflammation or injury by directly recruiting neutrophils through BLT1, or by serving as a relay signal that sustains a chemotactic gradient, guiding neutrophil migration toward other chemoattractants, including formyl peptides or C5a

One significant event, the Great Oxidation Event (GOE), marked the period of time in which oxygen became a major component of Earth's atmosphere and surface ocean

S5E), although analysis of hepatocellular injury and serum AST and ALT levels showed a significant increase compared to Gclc WT mice (Fig