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The results of Wound-healing assay and Transwell invasion assays showed that RRM2 overexpression significantly enhanced the migration and invasion ability of TPC-1 cells, while knockdown of RRM2 produced the opposite effect

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As the common oxidant, the intermediate of Fe(IV) = O, which usually presents in the catalytic cycle of natural oxidases, is considered as the active transient state

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Currently, it has been established that several probiotics, such as VSL#3, are beneficial in the treatment of UC and can alleviate the symptoms of UC by reducing the inflammatory response and immune response