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Phase 3 results expected this year will provide more comparable data

Cells adapt to serine deprivation via the de novo serine synthesis pathway (SSP), which diverts glycolytic intermediates (e.g., 3-phosphoglycerate) into serine biosynthesis under PKM2 inhibition [19, 20]

Rat Under normal physiological conditions, endogenous CoQ 9 in rat liver tissue is predominantly located in the mitochondrial subcellular fraction [183]