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Under the hypoxic, nutrient starvation and oxidative stress environment of CKD, the expression levels of BNIP3 and NIX are significantly upregulated

Effect of Pirfenidone on Proliferation, TGF--Induced Myofibroblast Differentiation and Fibrogenic Activity of Primary Human Lung Fibroblasts

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In another study, the knockdown of CD44v6 containing isoforms in colorectal cancer cells resulted in a significant decrease in BECN1 levels, further validating the results obtained in the previously mentioned study (Wang et al., 2019

Foods containing Glutathione: Asparagus, avocados, spinach, and okra have a high content of this antioxidant when consumed in their raw form

Citations & References: [1] Shi N, Yang Q, Zhang H, et al. Restoration of dystrophin expression in mice by suppressing a nonsense mutation through the incorporation of unnatural amino acids. Nat Biomed Eng. 2022;6(2):195-206. doi:10.1038/s41551-021-00774-1(IF:25.671)