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doi: 10.1172/JCI109981 166

Termination of autophagy and reformation of lysosomes regulated by mTOR

Some people have a mutation in the gene that controls this enzyme, which prevents it from breaking down certain chemicals properly

doi:10.1016/0168-9452(86)90016-6

4-48 h) regulates the expression of p53, cytochrome c and RBBP6 proteins, thereby inhibiting the apoptotic pathway in MRC-5 normal lung fibroblasts, while upregulating the expression of pro-apoptotic proteins in RMG-1, A549 and MDA-MB 231 cancer cell lines [1]