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It is suspected that reduced levels of NAD+ in the elderly may have a role to play in the reduction in renal function

10.1016/0022-1759(80)90340-3 209 PinzaruA

J Exp Biol 201:12031209 Ganini D, Petrovich RM, Edwards LL, Mason RP (2015) Iron incorporation into MnSOD a (bacterial Mn-dependent superoxide dismutase) leads to the formation of a peroxidase/catalase implicated in oxidative damage to bacteria