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Irrespective of its mechanism of action, cuprizone is a widely utilised and validated toxin for modelling CNS demyelination that is not directly associated with peripheral autoimmunity 20

The mean body mass index (BMI) was 22.28 kg/m 2 (21.43 for females and 23.99 for males), with a standard deviation of 2.79 kg/m 2 , indicating a relatively homogeneous distribution of BMI values across the cohort (Table 1)

At small volumes, reading from the wrong part of the meniscus can change your dose by a full unit

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Sodium losses in sweat are greater than any other electrolyte

A long-acting amylin could fit that bill