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These mediators include the inflammasome complex NOD-like receptor thermal protein domain associated protein 3 (NLRP3), and tumor necrosis factor-alpha (TNF-), which in turn exacerbate the dendritic and synaptic impairments leading to neuronal death and promote AD progression [13,14,15]

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Glutathion comp liefert Dir aktives Glutathion (GSH) in reduzierter Form direkt verfgbar fr Deine Zellen

Excess reactive Fe 2+ as LIP can cause ROS accumulation through Fenton reaction (Yan et al

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Chemical reagents Unless otherwise stated, all chemical compounds were purchased form Sigma (Gillingham, Dorset, UK)