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Therapeutic phlebotomy lowers hematocrit but also depletes iron stores

In a randomized clinical trial, the antioxidant astaxanthin, in combination with collagen peptides, improved facial skin elasticity and hydration and reduced matrix metalloproteinase expression while increasing endogenous collagen expression 54 , suggesting enhanced collagen homeostasis

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For patients who are newer to peptide therapy, older patients whose pituitary GH output has declined significantly with age, or those who prefer a more conservative starting protocol, Sermorelin is an excellent foundational choice before transitioning to the more potent CJC-1295/Ipamorelin stack