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Certain individualssuch as those with a history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2should not use GLP-1 receptor agonists

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Vitamin B12 oral forms are available without a prescription

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Inadequate function of methionine synthase can lead to an accumulation of homocysteine, which has been associated with increased risk of cardiovascular disease and age-related neurodegenerative disease (e.g., Alzheimers disease)