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165 Both -HB and acetoacetate bypass glycolysis to reduce acetyl-CoA, which can then be channeled into the Krebs cycle, and can thus increase energy availability in the brain

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Br.J Pharmacol 134: 737744, 2001

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doi: 10.3390/nu14030534 44

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consequently, extrahepatic manifestations related to this mutation (diarrhoea, fever) are scarce compared to those related to ATP8B1 [55]

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