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Inflammation in intervertebral disc degeneration and regeneration

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Disease stage effects: Early disease with substantial functional tissue responds better than end-stage with minimal viable cells

These neurotrophic factors help to promote the regeneration of nerves in the skin in response to injury

This finding is consistent with the inverted U-shaped hypothesis of motor-cognitive interaction and the catecholamine theory (Terry McMorris and Hale, 2012)