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Polyphenols are found to have modulatory effects on mitogen-activated protein kinases (MAPKs), NF-B, phosphatidylinositol 3-kinase (PI3K/Akt), and Wnt/-catenin networks and prevent the occurrence of inflammatory disorders (Jantan et al., 2021)

Yes, the cortisol gut microbiome connection matters because gut bacteria help regulate estrogen metabolism, cortisol balance, inflammation, and emotional stability, all of which change during menopause

Trends Immunol (2019) 40(11):103552

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