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These may be scarcely avoidable, given the need to assume a very large amount of trofinetide per day

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There is considerable regional and cell type variability of glutamate transporters.Cerebellar astrocytes have similar K m values for glutamate uptake relative to other brain regions (~50 M), however the Vmax of these astrocytes is the lowest of all brain regions studied (2.2 nmol/min/mg protein vs