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Although rare under physiological conditions, their numbers increase with age and are remarkably elevated in neurodegenerative disorders ( + T cells in the aging white matter (Kaya et al., 2022)

J hazard mater (2022) 424:127629

G., Haanm Ld., Spenkelink B., Awad H

5.2 Metabolic dysfunction-associated steatotic liver disease MASLD has emerged as a prominent global health challenge due to its asymptomatic manifestations, high prevalence and potential intra and extrahepatic consequences, often concurrent with the prevalence of obesity and T2DM and is a major cause of liver-related morbidity and mortality (Anonymous, 2025)

MS spectra were acquired between 3501,250 m/z (molecular weight/valency) in high-resolution mode (40,000 resolution for full scans and 20,000 resolution for MS/MS scans) with a rolling collision energy using a 250 ms accumulation time/spectrum and 50 mDa mass tolerance, and the 10 most intense precursors per cycle were selected for fragmentation with a dynamic exclusion time of 30 s

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