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In addition, the single-centre design may limit the generalisability of the findings to other settings and populations

If you become pregnant during treatment, discontinue immediately and consult your OB

Thirdly, sleep deprivation activates the renin-angiotensin-aldosterone system (RAAS), resulting in increased aldosterone and angiotensin II secretion (152), which may contribute to oxidative stress damage within the HPG axis

Some B12 supplements may also include aluminum, which is more likely to build up in the body when someone has kidney disease

Nutrients 14(4):819

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