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Alpha-synuclein is involved in manganese-induced ER stress via PERK signal pathway in organotypic brain slice cultures

MOTS-c enhances memory formation and protects against neuroinflammation, with benefits observed in Alzheimers and metabolic dysfunction models [6]

Tetrahedron 73 , 49134917 (2017)

Iron uptake, when NMDA receptors are stimulated, serves to generate RyR-mediated calcium signals through the production of ROS [174]

Wound studies report 9-fold increases in collagen content with GHK-Cu treatment compared to controls

Interestingly, the nature of NO as an endothelial-derived relaxing factor was initially not universally accepted because of these reactions: the reasoning of many researchers in this field was that the presence of a highly efficient scavenger in direct vicinity of the main source of NO would produce a concentration gradient leading to diffusion of NO into the blood stream (instead of into the smooth muscle) and thereby prevent vasodilatory function