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GPX4 activity depends on GSH and selenium levels, which also affects either the Grx system (GSH-dependent activity of Grxs) or the Trx system (selenium-dependent activity of TrxR)

Mitra S, Behbahani H, Eriksdotter M

Wu A, Feng B, Yu J, Yan L, Che L, Zhuo Y et al

A naturally occurring copper-binding tripeptide (Glycyl-L-Histidyl-L-Lysine) found in human plasma, studied for effects on wound healing, collagen synthesis, antioxidant activity, skin remodelling, and anti-inflammatory markers (investigational)