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JAMA Internal Medicine

2 Grip Strength and Exercise Endurance in Aged Mice Dimet-Wiley et al., Scientific Reports (2024) This study compared 5-Amino-1MQ treatment, voluntary wheel-running exercise (PoWeR), and combined treatment in aged C57BL/6J mice

Additional investigations suggest potential effects on insulin sensitivity, hepatic lipid accumulation, and inflammatory signaling, although these findings remain under active investigation and should not be interpreted as established therapeutic outcomes