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Description

Lactiplantibacillus plantarum strengthens the intestinal barrier: involvement of the endocannabinoidome

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Many elements related to the metabolic profile of cell senescence in specific disease mechanisms, cellular players, disease phenotypes, and response to current therapies are open fields of research from the basic, clinical/translational, and pharmacological standpoint (Table 7)

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Mitochondrial dysfunction is characterized by a deficient production of energy, a failure in calcium homeostasis, an activation of proteases and phospholipases, activation of nitric oxide synthase, and an abundant generation of free radicals [14, 15, 16]

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